Treatment of triple-negative breast cancer 2019. Explained.
Each person’s cancer is different, so the decision of treatment for triple-negative breast cancer is made by oncologist and the patient, patient’s abilities to tolerate the drug is taken into account.
here are the drugs:
Doxorubicin/ Adriamycin or Rubex. It s classified as an “anthracycline antibiotic.” Cancer cells no longer have the normal checks and balances in place that control and limit cell division, they divide fast and do not die. the drug work by damaging the DNA that tells the cell how to copy itself in division. If the cells are unable to divide, they die.
Cytoxan (cyclophosphamide) is a drug chemically related to the nitrogen mustards. Drug blocks tumor growth by cross-linking guanine bases in DNA double-helix strands – directly attacking DNA. This makes the strands unable to uncoil and separate. Cell can not reproduce and eventually will become old and die.
Taxol prevents the contraction and straining of the microtubule, inactivating them, Cell is not able to divide.
5-FU blocks thymidylate synthase (TS) inhibitor. Interrupting the action of this enzyme blocks synthesis of the pyrimidine thymidine, which is a nucleoside required for DNA replication. No replication means no new cell formation.
Antiandrogen drugs work by blocking the effects of androgens, such as testosterone and dihydrotestosterone from mediating their biological effects: growth and reproduction of cells.