Cholesterol | Wikipedia audio article

This is an audio version of the Wikipedia Article:

00:01:01 1 Physiology
00:03:44 1.1 Function
00:06:46 1.2 Biosynthesis
00:08:51 1.3 Regulation of cholesterol synthesis
00:11:35 1.4 Dietary sources
00:15:39 1.5 Plasma transport and regulation of absorption
00:20:55 1.6 Metabolism, recycling and excretion
00:23:36 1.7 Research
00:24:30 2 Clinical significance
00:24:40 2.1 Hypercholesterolemia
00:31:28 2.2 Hypocholesterolemia
00:33:19 2.3 Cholesterol testing
00:33:29 3 Interactive pathway map
00:34:08 4 Cholesteric liquid crystals
00:34:17 5 Stereoisomers
00:35:38 6 See also
00:35:48 7 Additional images
00:35:56 8 References
00:36:06 9 External links
00:36:32 undefined
00:36:42 undefined
00:37:02 undefined
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“The only true wisdom is in knowing you know nothing.”
– Socrates


Cholesterol (from the Ancient Greek chole- (bile) and stereos (solid), followed by the chemical suffix -ol for an alcohol) is an organic molecule. It is a sterol (or modified steroid), a type of lipid molecule, and is biosynthesized by all animal cells, because it is an essential structural component of all animal cell membranes.
In addition to its importance for animal cell structure, cholesterol also serves as a precursor for the biosynthesis of steroid hormones, bile acid and vitamin D. Cholesterol is the principal sterol synthesized by all animals. In vertebrates, hepatic cells typically produce the greatest amounts. It is absent among prokaryotes (bacteria and archaea), although there are some exceptions, such as Mycoplasma, which require cholesterol for growth.François Poulletier de la Salle first identified cholesterol in solid form in gallstones in 1769. However, it was not until 1815 that chemist Michel Eugène Chevreul named the compound “cholesterine”.


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