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What is doxycycline?
Doxycycline is an antibiotic medication used to treat pneumonia and other infections.
The trade name for doxycycline is Vibramycin.
Mechanism of action
Bacteriostatic. Inhibitor of bacterial protein synthesis by binding to ribosomal subunit 30S.
Therapeutic Indications, uses and benefits
– Treatment of the following infections caused by sensitive microorganisms: atypical pneumonia caused by Mycoplasma pneumoniae and Chlamydia pneumoniae; psittacosis; uncomplicated urethritis; venereal lymphogranuloma; inguinal granuloma (donovanosis).
– Helping in the treatment of severe acne vulgaris.
– Prophylaxis of: malaria caused by Plasmodium falciparum.
Modified release forms: reduce papulopustular lesions in adults with facial rosacea.
1) Adults and children over 8 years of age with weight over 45 kg. 1st day: 200 mg in single dose or 100 mg/12 h; maintenance: 100 mg/24 h, severe infection: 100 mg/12 h.
Modified release forms. Adults, including elderly patients: 40 mg/day.
Warnings and precautions
Do not use, except in children under 8 years of age, 2nd half of pregnancy and lactation; monitor overinfection by resistant microorganisms; precaution in patients with: history of predisposition to develop candidiasis, myasthenia gravis and hepatic alterations.
Anaphylactic reaction (including angioedema, exacerbation of systemic lupus erythematosus, pericarditis,; purpura Schönlein-Henoch and urticaria); headache; nausea, vomiting; photosensitivity reaction, rash including erythematous and maculopapular rash.